A study published in The International Journal of Surgery illustrated that peroperative local anesthetic administration methods were highly efficacious to prevent pain following laparoscopic cholecystectomy in comparison with the control group in which no local anesthetic was applied. In addition to minimizing postsurgery pain, these methods decreased the requirement for postsurgery analgesics and improved patient satisfaction.

This randomized controlled trial was carried out to investigate the impact of local anesthetic application methods in postoperative pain management in people undergoing laparoscopic cholecystectomies for cholelithiasis. The study incorporated 160 participants (aged 18-74 years) and segregated them into 4 groups: (i) local anesthetic injection (LAI) group, (ii) transversus abdominis plane block (TAPB) group, (iii) intraperitoneal local anesthetic injection (IPLA) group, and (iv) control group without any intervention.

The impact of these methods on postsurgery pain, patient satisfaction, requirement for additional analgesics, and length of hospital stay was determined. Visual Analog Scale (VAS) values at one, two, four, six, twelve, and twenty-four hours in the control group were substantially greater when compared to the LAI, IPLA, and TAPB groups.

Moreover, these VAS values were remarkably greater in the IPLA group  in comparison with the TAPB and LAI groups. Regarding VAS values at 1, 2, 4, 6, and 24 hours, no profound differences were noted between the LAI and TAPB groups. The VAS values at 12 hours in the LAI group were considerably greater when compared to the TAPB group.

Thus, the local anesthetic application methods can effectively alleviate postsurgery pain in laparoscopic cholecystectomies.