According to a restrospective analysis of 247 patients who underwent thyroidectomy, the occurence of intraoperative hypotension was associated with postoperative nausea and vomiting (PONV), as assessed via AUC-s100%. This outcome was based on the assumption that intraoperative hypotension during general anesthesia may be reason for PONV.

The baseline value was considered as the initial blood pressure (BP) determined prior to the initiation of anesthesia. Systolic BP evaluated during the surgery, from the beginning to the end of anesthesia was obtained from the anesthetic records. The time integral value was noted when the measured systolic BP fell lower than the baseline value and were regarded as area under the curve (AUC) of s100%.

As found, PONV was observed in 88 patients (35.6%) out of 247 patients under consideration. The univariate and multiple logistic regression analysis interpreted that total intravenous anesthesia (TIVA), history of smoking, and AUC-s100% were notably linked with PONV.