EN | RU
EN | RU

Help Support

Back

Study provides insights into the analgesic efficacy of Nefopam after laparoscopic colorectal cancer surgery

Study provides insights into the analgesic efficacy of Nefopam after laparoscopic colorectal cancer surgery Study provides insights into the analgesic efficacy of Nefopam after laparoscopic colorectal cancer surgery
Study provides insights into the analgesic efficacy of Nefopam after laparoscopic colorectal cancer surgery Study provides insights into the analgesic efficacy of Nefopam after laparoscopic colorectal cancer surgery

What's new?

Nefopam 80 mg does not offer superior advantages as an adjuvant in fentanyl PCA during the acute postoperative phase.

According to a novel study published in ‘Journal of Clinical Medicine’, the use of fentanyl patient-controlled analgesia (PCA) with nefopam 80 mg as an adjuvant did not have a higher analgesic effect following laparoscopic colorectal cancer surgery.

Postoperative pain poses as a clinical challenge in laparoscopic surgical procedures and perioperative management. This retrospective study evaluated the effectiveness of nefopam as an adjuvant in PCA for severe post-operative pain in patients undertaking the laparoscopy for colorectal cancer (also known as bowel, colon cancer, or rectal cancer).

The medical records of 120 patients were divided into 2 groups with 60 patients each in nefopam group (patients who were administered 80 mg of nefopam as an adjuvant in fentanyl PCA) and non-nefopam group (patients who were not administered 80 mg of nefopam). A thorough evaluation of data (concerning demographic, clinical features, and anesthetic; pain severity and opioid usage) at the postoperative anesthesia care unit (PACU) was done.

As revealed, there was no difference in the pain score and opioid administration at the PACU or on 1st, 3rd, or 5th day of the surgery. No difference was observed in case of day of PCA cessation, time to pass flatus, hospital stay duration, and occurrence of nausea/vomiting, dizziness, and headache.

Future studies are required to determine a safe and effective dose administration routine for nefopam to be used as an adjuvant to fentanyl or other opioid pain medications in PCA, noted the study researchers.

Source:

Journal of Clinical Medicine

Article:

Analgesic Efficacy of Nefopam as an Adjuvant in Patient-Controlled Analgesia for Acute Postoperative Pain After Laparoscopic Colorectal Cancer Surgery

Authors:

Eun Jung Oh et al.

Comments (0)

You want to delete this comment? Please mention comment Invalid Text Content Text Content cannot me more than 1000 Something Went Wrong Cancel Confirm Confirm Delete Hide Replies View Replies View Replies en ru
Try: