In adult patients undergoing root canal filling, gutta-percha/bioceramic sealer (BCS) was linked with considerably reduced short-term postsurgery pain, and with a trend for reduced analgesic intake and flare-up occurrence, as compared to gutta-percha/traditional sealer (TS, resin-based sealers), as per the findings of a systematic review and meta-analysis published in The Journal of Clinical Medicine. Researchers undertook this study to investigate the postoperative pain after root canal filling with BCS vs. TS techniques.

A search of electronic databases for the randomized trials yielded 682 records. The subgroup assessments were carried out for analgesic consumption, flare-ups, postsurgery time (24/48 hours), pulp status, and retherapy. Overall, 9 studies were chosen. BCS was linked with considerably lower postoperative pain vs. TS at 24 hours and 48 hours.

Furthermore, non-significant trends favoring BCS for analgesic consumption at 24 hours, flare-ups and obturation techniques at 24 hours and 48 hours, non-significant trends for reduced postsurgery pain with TS vs. BCS 24 hours and 48 hours in vital teeth, and for reduced postsurgery pain with BCS vs. TS in non-vital teeth at 24 hours and 48 hours were witnessed.

The postoperative pain was numerically reduced with TS vs. BCS at 24 hours and 48 hours following retherapy. Furthermore, the postsurgery pain did not vary between fillers when the therapy was over single or multiple visits. Thus, postoperative pain was considerably reduced after root canal filling with BCS compared with resin-based sealers.