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Administration of a local anesthetic solution (2% Lignocaine with Adrenaline) combined with Buprenorphine for intraoral block related procedures significantly reduces pain following surgical extraction of mandibular third molar.
A prospective, randomized controlled study depicted that a combination of local anesthetic solution and Buprenorphine during intraoral block procedures was an effective and safe pain management approach. Researchers aimed to compare Buprenorphine and 2% Lignocaine with Adrenaline in providing postsurgical pain relief after mandibular third molar extraction.
The study enrolled a total of 40 participants, who were randomized to either Group A or Group B, with 20 subjects in each group. For inferior alveolar nerve block, Group A was given a combination of 2% Lignocaine with 1:80,000 Adrenaline and Buprenorphine, while Group B was administered 2% Lignocaine with 1:80,000 Adrenaline.
The data was gathered and entered into a Microsoft Excel spreadsheet, then analyzed using SPSS software, version 21. The data was compared using Student's t-test, with a significance level set at 0.05. The combination of a local anesthetic solution and Buprenorphine was promising in the induction of postoperative analgesia without significant side effects in individuals undergoing molar extraction surgery.
Journal of Advanced Medical and Dental Sciences Research
A comparative study to appraise the efficiency of Buprenorphine and 2% Lignocaine with Adrenaline in induction of post operative analgesia following surgical extraction of mandibular third molar
Maroofa Hafiz et al.
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