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It is now
evident that human brain delineates the persistent pain as an important
manifestation of chronic pain.
"Using electroencephalography (EEG) as a noninvasive approach, the assessment of ongoing pain has become feasible and effortless", appeared from the report published in the journal Human Brain Mapping. Chronic pain marked with ongoing pain and diverse range of cognitive, affective and sensory abnormalities affects approximately 20% to 30% of the population. The management of this health trouble is somewhat difficult due to the lack of knowledge regarding its neural mechanisms.
For the purpose of assessing, a total of 31 chronic
back pain cases were selected and asked to rate the ongoing pain while also
recording EEG concurrently. According to the reports of time-frequency
analysis, ongoing pain intensity and prefronal beta as well as gamma
oscillations exhibited a positive relationship, whereas, alpha/beta oscillation
showed no associations. All these outcomes markedly showed that neuronal
oscillations involved in subjective perception rather than objective
nociceptive input exhibit ongoing pain as a major manifestation of chronic
pain. Therefore, the dissociation of pain intensity in chronic back pain cases
from nociceptive processing is supported. However, the study proposed that
investigation of the role of prefrontal gamma activity as an indicator of
ongoing pain in prognosis and management of chronic pain should be conducted in
future.
Human Brain Mapping
Prefrontal gamma oscillations reflect ongoing pain intensity in chronic back pain patients
Elisabeth S. May et al.
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