The patients with nonsurgical endodontic retreatment in the single visit exhibited fewer rates of post-operative pain instead of two visits. This conclusion was drawn from a randomized controlled trial done from one day to one month. With the proper care, root canal treatment is one of the best method to keep the teeth healthy for a longer time. But in some cases the tooth doesn't heal appropriately and may lead to pain, even after years of the treatment. It leads to further treatment to reduce pain.

This Randomized Clinical Trial was intended to estimate the comparative benefits of single and two visits of non-surgical endodontic retreatments with two distinct intracanal medicaments to reduce postoperative pain. One hundred and fifty patients who needed retreatment were randomized into three groups; group one (single visit), group two and three with calcium hydroxide and chlorhexidine (CHX) in different visits. The pain was assessed on 1st, 2nd, 3rd, 7th day and at one month following the therapy. All 2-visit treatments were performed one week next to the initial visit. Kruskal-Wallis, Pearson chi-square tests and Mann-Whitney were used to examine the data.

On the first day of assessment, group one exhibited lower postoperative pain as compared to CHX group (P ≤ .05). On the second day, group one significantly presented lower postoperative pain as compared to the other two groups (P < .05). On the third and seventh day, no considerable difference was noticed. At one month of evaluation, both group two and three exhibited higher postoperative pain as compared to group one. These findings presented single-visit retreatment is more beneficial than other groups.