Categories
Change Password!
Reset Password!
Comprehending microbiome differences in children with food allergies highlights Collinsella as a biomarker and supports microbiome-targeted therapies.
A new pilot study published in “Nutrients” Journal has uncovered increased gut and skin bacterial diversity in children with food allergies compared to their non-allergic peers. Importantly, these microbiome patterns evolve over time and differ across various food allergies, offering new insights into the complex relationship between food allergies and microbial health.
This finding is based on a study aimed to characterize changes in the gut and skin microbiomes of children under two years old with newly diagnosed immunoglobulin E (IgE)-mediated food allergy. The study also sought to examine how these differences change across diverse allergy types and over a period.
As part of a larger ongoing multicenter cohort, researchers followed 23 children with food allergy. The samples of feces and skin swabs were gathered at the time of diagnosis and after a year. Using bacterial 16S rRNA sequencing, researchers analyzed the hypervariable v1-v2 region to identify microbial diversity and community composition.
Key Findings:
The gut and skin microbiomes of children with IgE-mediated food allergies are not static but evolve alongside their clinical course, as implied. The study underscores the possible role of microbiome diversity and distinct bacterial genera, like Collinsella in affecting the development and severity of food allergies.
Nutrients
Characterization of the Gut and Skin Microbiome over Time in Young Children with IgE-Mediated Food Allergy
Michèle S Roth et al.
Comments (0)