According to a recently published meta-analysis, reduced NIH-CPSI scores and treatment considering CP/CPPS, a psycho-neuromuscular condition were found to be significantly related to each other.

CP/CPPS disorders show resistance against conventional urologic approaches like alpha-blockers, analgesics and antibiotics. As per a prescription, CPPS/ CP is a psycho-neuromuscular disorder due to psychosocial stress and protective pelvic floor guarding.

Rodney U.Anderson and colleagues conducted the meta-analysis to determine cognitive behavioural therapy, physical therapy and biofeedback efficacy in CPPS/ CP management. The data was collected from search engines Google Scholar, Cochran Library and PubMed from inception to December 2017. The keywords used during the search were pelvic pain, prostatitis, biofeedback, cognitive behavioural therapy or myofascial trigger point release. The analysis assessed the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) scores before and after the treatment.

A total of eight studies involved 280 patients selected for the analysis, which include sample sizes ranged from 8 to 116 men and treatment duration from 8 to 26 weeks. The CPSI noted before treatment was 21.7 to 33.5. After the procedure, 8.8 points non-standard weighted mean reduction in CPSI scores were noticed from baseline (p<0.001). Little heterogeneity among the studies was seen (I2 statistic = 18.5%). Further, an additional multimodal intervention study of 100 patients involved a sensitivity analysis also exhibited the same outcomes. The CPSI score with 6-point reduction showed significant improvement in disease condition, which concludes that introducing CPPS/ CP as psycho-neuromuscular disorder helps to reduce disease-related symptoms.