Ketorolac tromethamine and Dexamethasone emerge as viable options for post-endodontic management, as mentioned in a study issued in Cureus.

Dental patients often experience pain after undergoing endodontic therapy, prompting the need for effective pain management strategies. To address this issue, Reshma M. Sekhar and colleagues step forward to compare the efficacy of intramuscular injections of Dexamethasone and Ketorolac tromethamine against a placebo in reducing post-treatment endodontic pain.

The research involved 90 patients diagnosed with symptomatic irreversible pulpitis (dental pulp inflammation). Non-surgical endodontic therapy was performed in a single visit, followed by random assignment of patients into 3 groups for intramuscular drug administration: Group 1 received a saline solution, while Group 2 received Dexamethasone, and Group 3 received Ketorolac. Pain intensity was measured using a verbal rating scale both before and after the procedure, with pain levels recorded at 4 hours, 24 hours and 48 hours afterwards.

The results of the study demonstrated a significant reduction in pain scores across all three groups compared to preoperative levels. Notably, Dexamethasone and Ketorolac tromethamine exhibited particularly promising results at the four-hour mark post-treatment. Of the three, Dexamethasone showed significant pain reduction after 24 hours, but all three groups witnessed a gradual decrease in pain levels after 48 hours.