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Identifying pregnant women at risk for adverse pregnancy outcomes can be achieved through screening their serum levels of 25(OH)D.
An optimized intelligent Bayesian network algorithm analysis of a stratified randomized controlled field trial depicted that vitamin D levels of pregnant women at delivery can directly impact the method of delivery and indirectly influence maternal complications like preeclampsia and preterm delivery, increasing the likelihood of a cesarean section. Mina Amiri et al. aimed to understand the interplay between different factors influencing the relationship between the concentration of 25-hydroxyvitamin D [25(OH)D] at delivery and the delivery mode.
Researchers conducted a secondary analysis which involved a stratified randomized controlled trial with 1649 eligible pregnant women, who received vitamin D supplementation. To assess the relationship between various influential factors related to maternal vitamin D levels and the method of delivery, the researchers employed the Bayesian Network method.
According to the findings of the optimized intelligent Bayesian Network algorithm, women who had moderate (35.67%) or severe (47.22%) vitamin D deficiency at delivery were more likely to have a C-section compared to those with normal levels of this essential hormone (18.62%). The probability of experiencing preeclampsia was 1.5% for mothers with normal vitamin D levels, 14.01% for those with moderate deficiency, and 26.81% for those with severe deficiency.
Additionally, mothers with moderate (11.81%) or severe (27.86%) vitamin D deficiency had a higher likelihood of preterm delivery compared to those with normal levels (1.12%). The vitamin D levels of pregnant women at delivery can have a direct impact on the method of delivery and an indirect effect through maternal complications like preeclampsia and preterm delivery, resulting in a higher likelihood of cesarean section.
This study provides valuable insights into the role of maternal vitamin D deficiency in childbirth outcomes and could potentially inform strategies for optimizing maternal health and reducing the likelihood of cesarean sections. Healthcare professionals may consider monitoring and addressing vitamin D levels in pregnant women to promote healthier pregnancies and childbirth experiences.
Scientific Reports
Mode of delivery and maternal vitamin D deficiency: an optimized intelligent Bayesian network algorithm analysis of a stratified randomized controlled field trial
Mina Amiri et al.
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