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In patients with mild-to-moderate asthma, low-dose ginger supplement improves asthma symptoms and reduces inflammation.
In a new randomized trial, twice daily use of 1 g oral ginger ameliorated asthma control in mild-to-moderate asthmatics. The goal was to evaluate the efficacy of low-dose oral ginger in boosting subjective and objective measures of asthma control. A team of researchers conducted this 2-month double-blinded study involving 32 individuals with mild-to-moderate uncontrolled asthma. Volunteers were randomized to get either 1 g of ginger twice daily or a placebo, alongside their conventional asthma treatments.
Raised methacholine tolerance and reduced fractional exhaled nitric oxide (FeNO) concentrations were the key endpoints ascertained. Secondary endpoints were estimation of asthma control by the Asthma Control Test (ACT), Juniper mini Asthma Quality of Life Questionnaire (AQLQ), a 2-week symptom recall test, as well as measuring blood eosinophils and asthma-linked cytokines.
The study found that ginger supplementation did not affect levels of exhaled nitric oxide or blood eosinophils (common markers of asthma inflammation). However, significant improvements were observed in 3 different asthma symptom measures by the 28-day mark. Oral ginger also influenced asthma-associated serum cytokines, specifically interleukin (IL)-13 and IL-17A.
Hence, a modest daily dose of ginger as a dietary supplement can remarkably ease asthma symptoms and curb inflammation. These results highlight the need for further research using higher ginger doses in specific asthma endotypes to explore its potential as a novel therapeutic option.
Pharmaceuticals
Low-Dose Oral Ginger Improves Daily Symptom Scores in Asthma
Charles W. Emala et al.
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