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Labetalol stands out as the prime and safe choice for managing hypertension in pregnancy, minimizing risks for both mother and baby.
Even though Labetalol and Nifedipine were found to be equally effective in Preeclampsia, however, Labetalol outshined Nifedipine in terms of better tolerability and side effects profile in a recent study.
This prospective interventional study published in the Journal of Clinical & Diagnostic Research aimed to distinguish between Labetalol and Nifedipine administration concerning the side effects, obstetric complications and mode of administration.
A total of 200 pregnant Indian women with high blood pressure or hypertension after 20 weeks of gestation were considered. They were grouped as:
Their age, associated-side effects, pregnancy complications and mode of delivery (vaginal or caesarean) were compared. The details of study outcomes have been differentiated in the following table 1:
The outcomes between Group A and Group B did not vary significantly and were found to be equally effective, concluded the study researchers.
Journal of Clinical & Diagnostic Research
Comparison of the Efficacy of Labetalol and Nifedipine in Preeclampsia: A Prospective Interventional Study.
Neha Nimbark et al.
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