According to the findings of a study, a two-year Mediterranean diet intervention helped older people who were overweight or obese lose more weight and elicited a larger reduction in their fat mass percentage, waist circumference, and body mass index (BMI). Researchers aimed to evaluate the efficacy of a two-year multicomponent intervention for the management of obesity and overweight.

The intervention's impact on psychological health was also investigated. The subjects (n = 51) were randomly segregated into experimental and control groups. The experimental group were given group nutritional education sessions, personalized dietary-nutritional therapy based on a Mediterranean diet, and a program of physical activity, whereas the control group underwent written Mediterranean nutritional education.

In the experimental group, BMI and waist circumference, along with weight and fat mass percentage decreased more significantly. Both groups had improvements in their PHQ-9 depression scores. There was no discernible enhancement in either group's anxiety level (GAD-7) or adherence to the Mediterranean diet (PREDIMED).

The experimental group had a higher decline in waist circumference, BMI, weight and percentage of fat mass, after a two-year dietary nutritional intervention. At the end of the intervention, depression levels improved in terms of psychological well-being.