According to the investigators of the University of Turin and San Luigi Gonzaga Hospital of Orbassano, “the antegrade intramedullary nail is a minimally invasive therapy for proximal and diaphyseal humeral fractures operation with an accelerated improvement in range of motion, an immediate rehabilitation and tolerable pain. As the proximal and diaphyseal humeral fractures are not a rare event throughout the world, for its management is the surgical approach is a viable choice to decrease limb immobilization and improve functional ability to return to day-to-day activities.

This study determined the outcomes of intramedullary nail among the patients treated between January 2010 to December 2016 (with a minimum follow-up of 6 months). Subjects were assessed for postoperative complications, healing time, and functional recovery. Statistical analysis was performed by applying the t-test.

The analysis involved a total of 75 cases with diaphyseal and 20 cases with proximal fractures. Bone callus production a mean of 57 days following the operation. The overall functionality got improved with time and patients younger than 65 years showed better outcomes. No impact of patients' gender and type of fracture was seen over the consequences. A total of 18 cases required blood transfusions. No infections have occurred, and eventually, 10 cases went through revision surgery. All the study findings indicate that intramedullary nail is an effective treatment approach for proximal and diaphyseal humeral fractures.