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Ibuprofen
phonophoresis significantly reduces pain, stiffness and functional limitation,
therefore its use should be considered in management of knee osteoarthritis.
According
to a study published in Rheumatology International, the gel-based Ibuprofen
phonophoresis shows significant clinical efficacy in managing knee
osteoarthritis.
Ilke
Coskun Benlidayi and colleagues conducted a randomized, single-blinded,
comparative study to evaluate Ibuprofen
gel and cream phonophoresis effectiveness in patients suffering from knee
osteoarthritis. Phonophoresis is a way in which ultrasound is used to improve
the delivery of topical drugs. The selection of patients for this analysis was
based on American College of Rheumatology criteria. A total of 63 patients of
mean age 57.9 ± 9.7 years were assigned randomly either to Ibuprofen cream
or Ibuprofen gel group. Both groups went
through 10 sessions in two weeks. Visual Analogue Scale (VAS) and Western
Ontario and McMaster Universities Osteoarthritis Index (WOMAC) was used to
measure the main outcomes during analysis.
Both
groups reflected similar baseline VAS and WOMAC scores and showed an improvement in both VAS and WOMAC.
However, after application, the group received gel phonophoresis showed better
VAS and WOMAC scores as compared to cream phonophoresis (p < 0.001). The
results enlighten that gel Ibuprofen phonophoresis has better results than
cream form.
Rheumatology International
Comparative short-term effectiveness of Ibuprofen gel and cream phonophoresis in patients with knee osteoarthritis
Ilke Coskun Benlidayi et al.
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