Although High-intensity focused ultrasound (HIFU) had been known to provide short term symptom improvement of dysmenorrhea, but, a combination of HIFU and levonorgestrel-releasing intrauterine system (LNG-IUS) can be an effective long-term therapy for the same, a study published in Journal of Computer assisted Tomography ascertained.

This retrospective analysis was performed on 243 patients with acute adenomyosis to examine the effectiveness of HIFU plus gonadotropin-releasing hormone agonist or LNG-IUS in dysmenorrhea treatment. These patients were divided into:

• H group: PH group: Patients subjected to HIFU alone,
• H-G group: Patients subjected to HIFU and gonadotropin-releasing hormone agonist, and
• H-L group: Patients subjected HIFU and LNG-IUS

Following the therapy, a comparison of clinical results was done at 3 months, 6 months, and 1 year.

A noteworthy difference in effective rates of dysmenorrhea relief after 12 months, but not 3 or 6 months was observed:

Also, H group had substantial differences in dysmenorrhea efficacy amongst patients of various ages or ablation rates at 1 year after the therapy.