EN | RU
EN | RU

Help Support

Back

H. pylori infection may be linked with high risk of iron deficiency anemia in children

anemia_in_children anemia_in_children
anemia_in_children anemia_in_children

What's new?

Children suffering from H. pylori infection appear to be at higher risk of iron deficiency anemia.

A systematic review and meta-analysis published in The Journal of Pediatric Infectious Diseases revealed a link between Helicobacter pylori (H. pylori) infection and an elevated risk of developing iron deficiency anemia in children. Utilizing Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, investigators sought to find out the link between H. pylori infection and iron deficiency anemia risk.

Various databases were searched to find out the relevant studies. With the aid of the Modified Newcastle-Ottawa Scale,  the quality assessment of retrieved studies was done.  In total, 22 eligible studies (8 cross-sectional, 6  randomized control trials, 5 case-control, 2 surveys, and 1 cohort) with 4,455 controls  and 3,434 cases were incorporated.

In the random-effects model, H. pylori infection was reported to be linked with a greater risk of iron deficiency anemia  (odds ratio 1.70). According to the meta-regression assessment, none of the evaluated factors that may affect the prevalence of iron deficiency anemia attained statistical significance.

Substantial differences were reported between results when studies were categorized as per the methods used for H. pylori diagnosis and the level of incomes on the basis of World Bank classification. Thus, there may be an association between H. pylori infection and iron deficiency anemia risk in children. However, the GRADEpro Guideline Development Tool evidence for the risk of iron deficiency anemia was found to be of “moderate certainty.”

Source:

The Journal of Pediatric Infectious Diseases

Article:

The Association between Helicobacter Pylori Infection and Iron Deficiency Anemia in Children: A Systematic Review and Meta-Analysis

Authors:

Sara Z. Hamdan et al.

Comments (0)

You want to delete this comment? Please mention comment Invalid Text Content Text Content cannot me more than 1000 Something Went Wrong Cancel Confirm Confirm Delete Hide Replies View Replies View Replies en ru
Try: