Dexmedetomidine doses yield comparable results for awake intubation in oromaxillofacial and oral surgeries

Researchers have discovered that varying doses of dexmedetomidine offer comparable results for awake intubation in patients undergoing surgery for oromaxillofacial and oral malignancy. This finding is crucial for ensuring optimal airway management in individuals facing anticipated difficulties during surgery, as mentioned in a randomised, double-blind study published in the Indian Journal of Anaesthesia.

Overall, 90 patients (aged 18 to 60 years) were considered. They were randomised into 3 groups with varying doses of dexmedetomidine (0.5 µg per kg, 1 µg per kg and 1.5 µg per kg). The airway obstruction score was regarded as the primary outcome measure whereas intubation scores (coughing, movement of the limbs and vocals) and fibreoptic intubation comfort score were the secondary outcome measures. For assessing sedation, the Ramsay sedation score (RSS) was beneficial.

Results revealed no major changes in airway obstruction or intubation comfort scores among the groups. However, patients receiving the highest dose faced deeper sedation.