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Combining Dexketoprofen with Vitamin B delivers better pain relief and fewer side effects than Dexketoprofen alone for grade I-II cervical sprains.
Musculoskeletal disorders are a common reason people miss work, and NSAIDs are the usual recommendation. To find a solution, a recently published study investigated whether Dexketoprofen in combination with Vitamin B or alone is effective for grade I-II cervical sprains.
A double-blind, randomized study by Pamela Delgado-García and researchers compared two treatments:
Patients took the treatments every 8 hours for 7 days via oral route. Pain levels were estimated utilizing a visual analogue scale (VAS), and disability was assessed with the Northwick Park Neck Pain Questionnaire (NPQ). The FDC significantly reduced pain intensity and disability percentage compared to Dexketoprofen with fewer adverse events, as shown in Table 1:
The FDC of Dexketoprofen and B vitamins considerably reduced pain from the third day and sustained this relief throughout the 7-day treatment, as depicted in Figure 1:
Conclusively, the FDC of Dexketoprofen and B-vitamins outperforms Dexketoprofen alone in both effectiveness and safety for treating grade I-II cervical sprains.
Clinical Drug Investigation
A Randomized Control Trial of Dexketoprofen/Vitamin B (Thiamine, Pyridoxine and Cyanocobalamin) Fixed-Dose Combination in Post-Traumatic Grade I–II Cervical Sprains
Pamela Delgado-García et. al.
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