Choline intake benefits atherosclerotic cardiovascular disease risk patients

According to a recent study issued in the BMC Public Health, higher levels of Choline consumption (around 244 mg/day for females; 367 mg/day for males) are linked to a lower risk of developing atherosclerotic cardiovascular disease (ASCVD).

This study by Hui Lin et al. aimed to clarify the relationship between Choline intake and ASCVD risk in adults and assess Choline's impact on metabolic syndrome (MetS) and its components to understand dietary risk factors for ASCVD better. The data was collected from the National Health and Nutrition Examination Survey database.

All in all, 5525 people were included in the cross-sectional study. The individuals were segregated into two groups, ASCVD (5015 patients) and non-ASCVD (510 patients). Regression methods, both multivariable-adjusted and univariable, were used to examine the association between diet Choline and relevant factors. To assess the relationship between Choline and ASCVD, restricted cubic spline analysis and logistic regression analysis were employed.

The ASCVD participants had a higher intake of Choline than non-ASCVD patients. Men, married people, those who engage in intense physical activity, and those with higher levels of education made up the higher tertiles of Choline consumption as opposed to those who smoke and drink in the lower tertile. Lesser people in the increased Choline intake groups had a record of stroke and heart failure. Choline intake showed an inverse association with heart disease, stroke, and ASCVD. In men, there was a J-shaped connection discovered between Choline consumption and these ailments. Dietary Choline was not found to be associated with MetS.

The authors emphasized the need for future longitudinal studies to investigate the causal relationship between Choline intake and ASCVD.