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When used in conjunction with scaling and root planing, aloe vera gel serves as an effective and safe herbal alternative to tetracycline fibers for chronic periodontitis.
A randomized controlled clinical trial by Thakuria A et al. explored the usefulness of two subgingivally delivered adjunct therapies—tetracycline fibers and 100% pure aloe vera gel—used alongside scaling and root planing (SRP) to relieve chronic periodontitis. Researchers assessed the effectiveness of these treatments in improving key clinical parameters, such as probing pocket depth (PPD), plaque index (PI), and modified sulcular bleeding index (mSBI).
The trial enrolled 20 patients, each with multiple affected periodontal sites. A total of 60 sites were treated, with each patient randomly assigned to one of three groups for treatment in different quadrants:
Clinical parameters were gauged at 3 time points: baseline (prior to treatment), day 7 (1 week post-treatment), and 3 months postoperatively. As found, both tetracycline fibers and aloe vera gel proved to be effective adjuncts to SRP for tackling chronic periodontitis. Using 100% pure aloe vera gel and tetracycline fibers alongside SRP led to prominent improvements in PPD (P < 0.05) as opposed to SRP + saline irrigation.
Furthermore, the tetracycline group illustrated a substantial decrease in PI (P < 0.05) and pronounced reductions in the mSBI (P < 0.001) as opposed to the saline group. For clinicians, these findings highlight aloe vera gel as a promising, non-chemical, affordable option for adjunctive treatment in chronic periodontitis. This is particularly beneficial for those seeking herbal alternatives to traditional chemotherapeutic agents like tetracycline fibers.
Journal of Pharmacy And Bioallied Sciences
Comparative Evaluation of Subgingivally Delivered Tetracycline Fibers and Aloe Vera Gel as an Adjunct to Scaling and Root Planing in Treatment of Chronic Periodontitis: A Randomized Controlled Clinical Trial
Thakuria A et al.
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