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Previous fractures, prior falls,
poor BMD, and other factors associated with falls may help in identifying the
risk of fractures in elderly women with osteoporosis.
Osteoporosis is a severe disease of bones that weakens bones.
About 200 million women known to suffer from osteoporosis worldwide. There are
several known risk factors that cause long-term fracture risk. However, risk
factors that cause risk for a shorter time like over a 1-year period are less known.
For evaluating factors that involved in near-term risk of fractures (such as
hip fracture and any non-vertebral fracture), scientists a study. They used a
repeated-observations design and data that was taken from the Study of
Osteoporotic Fractures (SOF) for their study. A total of 2499 osteoporotic
women were involved in the study. The age of the women was ≥65 years. The
factors which were used to evaluate the near-term risk of fractures over the
1-year period were evaluated by using multivariable frailty models. These
potential predicting factors followed to each qualifying SOF exam before the
evaluation. Further, a corresponding risk-prediction tool was also established
for evaluation because of hip fracture discriminative ability.
Percentage of fractures in 1-year period successive to each exam was 6.6% for a
non-vertebral fracture and 2.2% for hip fracture. The independent
factors that were predictors of hip fractures were a prior fracture, low total
hip T-score, and risk factors for falls. Further, the independent factors that
predicted non-vertebral fracture were age, prior falls, prior fracture, total hip T-score, Parkinson’s disease or
stroke, walking speed, and smoking.
Therefore, various predictive factors of hip and non-vertebral fracture were
identified within a 1-year follow-up period among elder osteoporotic patients.
Further, a subset for hip fracture was involved in the risk assessment tool. An
assessment of these factors can help in evaluating treatment options for
osteoporosis by analyzing patients, which required an urgent need of treatment.
However, additional research is required to justify the findings of this study
the precision of the risk assessment tool.
Osteoporosis International
Predictors of near-term fracture in osteoporotic women aged ≥65 years, based on data from the study of osteoporotic fractures
D.Weycker et al.
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