Pain is the leading cause of suffering, disability and medical care worldwide. Pain associated with chronic diseases are not life-threatening, but people continue to live with this pain in developed and developing countries affecting their overall quality of life. The Global Burden of Disease Study 2013 indicated these as "years lived with disability" (YLD) for a broad range of disease and injuries in 188 countries. The results of the survey indicated chronic low-back pain as the major cause of YLD followed by the major depressive disorder. Other frequent causes of YLDs include a migraine, chronic neck pain, osteoarthritis, other musculoskeletal disorders and medication overuse headache.