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Ketorolac injection is used for short-term relief of moderate to severe pain. It is generally used before or after medical procedures or after surgery.
Ketorolac injection is used for short-term relief of moderate to severe pain. It is generally used before or after medical procedures or after surgery.
Ketorolac inhibits prostaglandin synthesis by competitive blocking cyclooxygenase (COX) enzyme. Ketorolac reduces the prostaglandins synthesis, chemicals that cells of the immune system, that cause the redness, fever, swelling and pain of inflammation and also effective to reduce non-inflammatory pain.
IV: 30 mg as single dose or 30 mg every 6hour; not to exceed 120 mg/day
Ketorolac is rapidly absorbed and mean peak plasma concentration of 2.4μg/ml at an average of 5.4 minutes after dosing. More than 99% of the ketorolac in plasma is protein-bound over a wide concentration range. The terminal plasma elimination half-life was 5.1 hours, average volume of distribution 0.15 l/kg, and total plasma clearance 0.35ml/min/kg. The primary route of excretion of ketorolac and its metabolites is renal: 91.4% (mean) of a given dose being found in the urine and 6.1% (mean) in the faeces.
Common (affecting between 1- 10 to 1 in 100)
Uncommon (affecting between 1-100 to 1 in 1000)
Very rare (affecting less than 1 in 10,000)
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