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Muslaxin combines Ibuprofen and Chlorzoxazone to alleviate skeletal muscle pain and spasms. Ibuprofen reduces inflammation, easing pain and swelling while Chlorzoxazone targets muscle spasms, enhancing mobility and further reducing pain.
Muslaxin combines Ibuprofen and Chlorzoxazone to alleviate skeletal muscle pain and spasms. Ibuprofen reduces inflammation, easing pain and swelling while Chlorzoxazone targets muscle spasms, enhancing mobility and further reducing pain.
This combination effectively addresses both inflammation-related discomfort and muscle tension, offering comprehensive relief for these conditions.
Pharmacological class: Muslaxin is a centrally acting muscle relaxant (spasmolytic) with analgesic effect.
Muslaxin is recommended for:
Ibuprofen is a phenylpropionic acid derivative belonging to the NSAID group. It works by reducing the production of prostaglandins in the body. This further leads to a reduction in inflammatory pain, swelling, and fever in humans. It also reversibly inhibits platelet aggregation.
Chlorzoxazone is a centrally acting medication used for treating musculoskeletal pain and improve muscle mobility. It primarily acts in the spinal cord and subcortical areas of the brain to block polysynaptic reflexes responsible for producing skeletal muscle spasms of various origins.
Additional Considerations:
Ibuprofen:
Absorption and Distribution:
Metabolism and Excretion:
Chlorzoxazone:
Absorption and Distribution:
Do not use Ibuprofen concomitantly with:
Muslaxin should be used with caution with the below medications:
Common side effects (This might affect 1 out of every 10 people):
Uncommon side effects (These may affect 1 in 100 people to 1 in 1000 people):
Very rare side effects (affecting less than 1 in 10,000 people):
In the most study by Putilina, M. V. (2024), the benefits of combining NSAIDs with a muscle relaxant like Muslaxin were found to be significant:
It's worth noting that Muslaxin can be used effectively without the need to identify specific patient groups, although its relevance increases when single-drug therapy is insufficient. In conclusion, Muslaxin exemplifies the rationale for using fixed combinations in pain management, highlighting their practical advantages in clinical settings. [1]
In another study by Patel et al. (2019), the combination of Chlorzoxazone and Ibuprofen proved to be an effective therapy for acute low back pain. Both medications were well-tolerated, making them valuable treatment choices for patients with this condition. [2]
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