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Knee osteoarthritis (OA) is a highly prevalent global health problem and associated with pain and functional disability during physical tasks and activities mainly in women. one of the basic the treatment recommended for OA is to increase the level of physical activity.

9min read    

Epidural labor analgesia is the common technique used for the management of labor pain. Ropivacaine has been often used for epidural labor analgesia, because of less motor block and stable hemodynamics. Dexmedetomidine possess sedative and analgesic properties without causing respiratory depressant effect and enhances local anaesthetic effects without increasing the incidence of side effects.

8min read    

 A recent randomized withdrawal trial showed that once-daily controlled-release formulation of pregabalin in patients with postherpetic neuralgia showed significant results.

10min read    

Ketamine mouthwashes found to be clinically meaningful and statistically significant reduction in pain scores. They have an acceptable safety profile and can be a useful adjunctive treatment in the multi-modal management of severe mucositis.

8min read    

A new form of exercise therapy named as painful exercises focused on loading and resistance programmes for temporary pain relief in patients with chronic musculoskeletal pain has found to offer significant benefit. In a systematic review and meta-analysis, the painful exercises were compared with non-painful exercises. For this review, two authors independently selected studies and appraised risk of bias. Methodological quality was determined by using the Cochrane risk of bias tool. The quality of evidence was assessed through the Grading of Recommendations Assessment system

7min read    
Key Take-Away:

Postherpetic neuralgia is a severe condition of pain arises amidst the nerves. This pain may affect the functioning of the nerves which can be improved by neuromodulation. This study illuminates the various methods of neuromodulation to counter neuralgia pain and suggests that peripheral nerve stimulation improved patients outcomes in postherpetic neuralgia.

Postherpetic neuralgia (PHN) is common in the United States. Current treatment options for PHN are fairly limited.

7min read    
Key Take-Away:

Osteoporotic fractures are one of the major causes of increased morbidity and mortality.

The risk of future fractures is further escalated with the previous fractures. This increased risk can be reduced by using anti-osteoporosis medications. In this study, persistence time of different types of anti-osteoporosis drugs have been compared, and it has been concluded that teriparatide and denosumab exhibit better persistence levels than alendronate.

The purpose of this study was to estimate real-world persistence amongst incident users of anti-osteoporosis medications.

8min read    
Key Take-Away:

Opioids are known to provide significant recovery and relief from pain after surgical operations like surgery of ankle fractures. However, the patients get addictive to opioid use. This study establishes that there exists no association between opioid intake and disability after surgical management of ankle fractures

Opioid-centric pain management strategies have created an epidemic of prescription opioid abuse.

8min read    
Key Take-Away:

Postherpetic neuralgia causes damage to sensory nerves causing severe neuropathic pain. The study evaluated that early treatment can manage the problem of pain in postherpetic neuralgia. It was a chronic university-based pain clinic study.

As herpes zoster progresses via postherpetic neuralgia (PHN) to well-established PHN, it presents its recalcitrant nature to the treatment.

7min read    
Key Take-Away:

Endometriosis is a chronic condition that induces dysmenorrhea, pelvic pain and infertility resulting in reduced quality of life in reproductive years of women. This double-blind, randomised study focuses on determining the dose-dependent effect of elagolix and establishes that both higher and lower dose of elagolix is effective in reducing dysmenorrhea pelvic pain in women with endometriosis.

Endometriosis is a chronic, estrogen-dependent condition that causes dysmenorrhea and pelvic pain. Elagolix, an oral, nonpeptide, gonadotropin-releasing hormone (GnRH) antagonist, produced partial to nearly full estrogen suppression in previous studies.

10min read    
Education

Sinusitis affects about 1 in 8 adults in the United States, resulting in over 30 million annual diagnoses.

American Academy of Otolaryngology-Head and Neck Surgery Foundation
15 min read    
Education

Chronic pain can be a serious consequence of surviving cancer. The prevalence of pain in cancer survivors has been reported to be as high as 40%.

American Society of Clinical Oncology
10 min read    
Education

Neuropathic pain is defined as the pain initiated or caused by a primary lesion, dysfunction, or transitory perturbation of peripheral or central nervous system.

Western Australian Therapeutic Advisory Group
2min read    
Education

Transitional care, as defined by the Society for Adolescent Medicine refers to the purposeful, planned movement of adolescents and young adults with chronic physical and medical conditions from chi

Ann Rheum Dis 2016;0:1–8
4min read    
Education

As per the World Health Organization (WHO), osteoporosis refers to a progressive systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of the bone tissues, w

Arch Osteoporos. 2017; 12(1): 43.
2min read    
August 17, 2018

Knee osteoarthritis (OA) is a highly prevalent global health problem and associated with pain and functional disability during physical tasks and activities mainly in women. one of the basic the treatment recommended for OA is to increase the level of physical activity.

Key Take-Away:

Postherpetic neuralgia is a severe condition of pain arises amidst the nerves. This pain may affect the functioning of the nerves which can be improved by neuromodulation. This study illuminates the various methods of neuromodulation to counter neuralgia pain and suggests that peripheral nerve stimulation improved patients outcomes in postherpetic neuralgia.

Postherpetic neuralgia (PHN) is common in the United States. Current treatment options for PHN are fairly limited.

7min read    
Education

Sinusitis affects about 1 in 8 adults in the United States, resulting in over 30 million annual diagnoses. Sinusitis is the fifth most common diagnosis in the world; more than 1 in 5 antibiotics prescribed in adults are for sinusitis. Irrespective of the high incidence and economic burden of sinusitis, significant practice dissimilarities exist through and within the numerous disciplines involved in managing the condition. The guideline is applicable for patients aged 18 years and above with a clinical diagnosis of uncomplicated rhinosinusitis.

American Academy of Otolaryngology-Head and Neck Surgery Foundation
15 min read